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V.MED CUT MIX 300mg
CATEGORY: Hybrid Injectables
CONTENT: Drostenolone Propionate 100 mg Trenbolone Acetate 100 mg Testosterone Propionate 100 mg
PRESENTATION SIZE: 10ml bottle
STRENGTH: 300mg per ml
TOTAL STRENGTH: 3000mg per 10ml bottle
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This product is a combination of the following three ingredients
When profiling this compound, we must look at the profile of every individual compound and then look at the synergistic effect of the three compounds together.
Testosterone Propionate is one of the many esterified variants of Testosterone available. It is an injectable compound with a slower rate of release than un-esterified Testosterone, but a faster rate of release than all other esterified forms commonly available. This is due to the larger Propionate ester attached to the Testosterone molecule. This augments the release rate and half-life of Testosterone to that of a faster release than other common esterified variants, such as Testosterone Enanthate or Testosterone Propionate. The majority of Testosterone products that have been designed are single products that contain a single esterified form (such as this one), as opposed to Testosterone products which consist of a blend of several different esterified variants in the liquid (such as Sustanon 250, for example). Testosterone that is un-esterified holds a very short half-life, making its use very inconvenient and impractical (Testosterone suspension is one such Testosterone product that consists of pure un-esterified Testosterone, and does not have an ester bonded to its structure). The Propionate ester expands Testosterone’s half-life to that of 4.5 days. Testosterone itself is considered the most natural and safest anabolic steroid any individual can use, and it is easily the most versatile and flexible anabolic steroid in terms of how it can be utilized in cycles and for different purposes and goals.
Testosterone Propionate’s details and information were first published and released in 1935 as a result of various methods to determine the best possible manner of maximizing the uses of Testosterone itself, because as mentioned above, Testosterone un-esterified possesses a very short half-life[1]. Shortly afterwards, Schering AG (located in Germany) began manufacturing and releasing on the market the very first Testosterone Propionate product under the trade name Testoviron, which is to this day still a very popular brand name. Testosterone Propionate was the very first esterified variant of Testosterone to ever be created, and is the oldest used esterified form of Testosterone dating back to the mid-1930s. Because of this, vast amounts of Testosterone Propionate was found among the prescription drug market in the United States, and was the most widely utilized form of Testosterone in the world until the 1960s. During the 1950s, Testosterone Propionate was but only one of 3 available anabolic steroids in existence (Testosterone suspension, Testosterone Propionate, and Methyltestosterone). Today there exist hundreds of anabolic steroid analogues. A little known fact as well is that Testosterone Propionate was also developed into a buccal and sublingual format that was not very popular and subsequently discontinued during the 1980s. Sublingual and buccal forms are tablets designed to be absorbed by the mucous membranes under the tongue (sublingual) as the tablet dissolves or by the mucous membranes between the surface of the gums and the cheek/lip.
Testosterone Propionate enjoyed a great amount of medical uses for various medical treatments shortly after its release. These included: treatment for male androgen deficiency (andropause or hypogonadism), treatment for sexual dysfunction, and treatment for menopause, treatment for chronic dysfunctional uterine bleeding (menorrhagia), treatment for endometriosis, and many additional countless medical applications. Eventually, as with all anabolic steroids, Testosterone Propionate’s approved medical treatments were eventually reduced by the FDA as a result of the increased control over the prescription drug market granted to the FDA by the United States government. Eventually, Testosterone would only be utilized for male patients.
Testosterone Propionate is a very popular anabolic steroid, and as such, enjoyed a very wide and common availability not only in the US market, but globally even today. This is due in large part, however, to the fact that for a long time the only Testosterone preparation available was Testosterone Propionate, and not because of preference. Later on, more convenient esterified forms of Testosterone were developed (Testosterone Enanthate and Testosterone Cypionate) which exhibited longer half-lives and windows of release, which therefore appealed to more individuals who preferred less frequent injections, which is what the later developed esterified Testosterone formats provided. Today Testosterone Propionate is still sold on the American prescription drug market, but its use is lower than it historically has been, and how much longer it will remain on the market is under question due to the more common use of other forms of Testosterone that have been developed that are more convenient and comfortable to use for most people.
As previously mentioned, Testosterone Propionate is simply Testosterone with the Propionate ester bound to the Testosterone chemical structure. Specifically ‘Propionate’ is Propionic acid, but once bound to Testosterone it is properly referred to in chemistry as an ester bond (or ester linkage). Propanoic acid is bonded to the 17-beta hydroxyl group on the Testosterone structure. Esterified anabolic steroids are more fat soluble, and release slowly from the injection site – however, this is not the main reason as to why esters extend the release rate of the anabolic steroid. The primary reason for the augmentation of its half-life and release rate is because once Testosterone Propionate enters the bloodstream, enzymes work to break the bond between the ester and the hormone, which takes a varying amount of time. The end result is that the ester is removed from the hormone by enzymes, and what is left is pure Testosterone that is free to do its work in the body. This process of enzymes cleaving off the ester from the Testosterone molecule is what is responsible for the slower release rates. Testosterone alone with no ester bonded to it possesses a half-life of approximately 2 – 4 hours. When the Propionate ester is attached to it, creating Testosterone Propionate, the half-life of Testosterone is now extended to 4.5 days, providing a slower release and activity of the hormone.
The properties of Testosterone Propionate are what any individual would expect from any other type of Testosterone preparation, with the exception of the differing release rates and half-life. Testosterone is what could be considered quite literally the original anabolic steroid, which is manufactured endogenously naturally in all humans and in the vast majority of animal species. Because of this, Testosterone is considered the safest anabolic steroid for use, as every individual’s body is already accustomed to the effects of Testosterone only to a lesser degree. Essentially, the use of Testosterone for the purpose of physique and performance enhancement is simply the supplementation of additional hormones – the act of inserting more of a hormone into the body that it already manufactures and uses.
Testosterone itself possesses a moderate level of Estrogenic activity, whereby it holds a moderate affinity to bind to the aromatase enzyme (the enzyme responsible for the conversion of Testosterone into Estrogen). Therefore, a moderate level of aromatization is to be expected with Testosterone use unless an aromatase inhibitor is utilized (such as Arimidex, Aromasin, and Letrozole) to inhibit the aromatase enzyme and therefore render it unable to aromatize any Testosterone into Estrogen. Therefore, Testosterone serves as a preferable compound for bulking but can also be utilized for cutting and fat loss phases as well. At the end of the day, however, Testosterone of any type is required in any cycle of any anabolic steroid if at least for the maintenance of proper physiological function of Testosterone in the body during a period in which the endogenous production of Testosterone has been suppressed or shut down from the use of anabolic steroids. Testosterone itself is also a very strong anabolic compound, suitable even on its own for any purpose, and is in fact suggested as the very first and only anabolic steroid that should be utilized in all first-time and beginner cycles.
Testosterone Propionate historically succumbed to the rumor among athletes and bodybuilders that it is better for cutting and fat loss phases, and many claimed that it provided less water retention than other esterified forms of Testosterone. This must be clarified as a large rumor and misunderstanding as a result of individuals developing improper conclusions not based on any proper scientific reasoning. As previously explained, the Propionate ester (or any ester affixed to Testosterone) is always broken off by enzymes in the body, after which 100% pure bio-identical Testosterone is left as a result. This Testosterone is then free to do its job in the body, and this occurs with all esterified forms of Testosterone. Therefore, the only possible augmentation that esterification has to Testosterone’s properties/effects are on its half-life and rate of release. If there is any difference in the actual reported experiences by different bodybuilders and athletes, it would most likely be extremely minimal, as the esters essentially only determine how much Testosterone is released into the bloodstream in any one given time frame.
As far as steroids are concerned, the king of them is testosterone. It’s not only endogenously produced inside of the body (that’s a fancy way of saying naturally made) but it is also produced in other parts of the body as well. That makes it extremely important to keep in mind because it is something that is naturally beneficial and worthwhile to supplement. If you’re someone that is sceptical as far as using a steroid for long-term use, you might want to consider testosterone, especially the propionate version of it due to its effectiveness for long durations as a highly bioavailable steroid. It not only provides a high level of focus and aggression with standard dosages, but it is also relatively lax as far as side effects are concerned, but be aware, side effects do exist and should be noted.
For one, because the body is so well-adjusted to testosterone, it should be noted that when it comes to the propionate version of it, it is one of the most studied steroids in the entire world. It was one of the first steroids synthesized for exogenous use of something endogenously produced, so because of that alone, the world of science and sport is well-aware of just how effective testosterone can be in the long term. It’s definitely something you should value if you’re looking to enhance your capability as a sportsman or simply someone looking to take their recovery efforts to the next level. It makes testosterone a worthwhile supplement to try. The reason for this is due to the fact the “blueprint” that composes testosterone is something the human body is already fairly accustomed with. In comparison to other kinds of blueprints or formulas, it is something that is otherwise not able to withstand the full payload that one might expect from a typical dosage.
Aside from that, the benefits of testosterone and the comparatively low side effects are great when you juxtapose testosterone with another sort of compound like trenbolone or something similarly toxic and damaging.
When it comes to steroids, undoubtedly the side effects that scare people the most are those related to estrogen and its side effects. This is very common when you consider the fact that as a man, the primary reason you have masculine features is due to higher levels of testosterone in comparison to estrogen. For women, the inverse is true. This is very important to understand because whenever you dose with an exogenous compound, you’re going to throw your hormone levels out of whack. This means that whenever you do engage in using one of these compounds, you have to understand that whenever you introduce higher levels of androgenic (testosterone producing compounds) compounds, these are going to result in feedback levels of estrogen in response. This is very important to keep in mind because otherwise, you will be unable to stave off the bad effects that you would otherwise experience from the compound.
One of the most popular reactions that one can have when injecting testosterone is the typical estrogenic side effects that you would get with any androgen. The primary one that most people are afraid of is gynecomastia. It’s a very common symptom in men as a result of the estrogenic imbalance, and while it is more popularly seen in boys that reach puberty, it is actually present in men of adult age as well, especially when they abuse or misuse androgenic compounds. But aside from gyno, it is also possible to develop symptoms similar to those in women who have very high estrogenic activity. This would include bloating, increased variance in emotional capacity (i.e. getting emotionally loud, demonstratively upset more often, a whole host of other problems). These are very important to note because without keeping an eye on them you would be unable to discern between emotion or the next. This is primarily why it’s so important to monitor your symptoms because if they get really out of control, it may be too late to stop them.
Thankfully, if you do encounter estrogenic activity, you should keep either an aromatase inhibitor (AI) or a SERM on hand. An AI will help reduce your serum estrogen levels, which is important if you want to actually reduce how much estrogen you have in your body. With a SERM, it serves as a way of blocking testosterone from binding to the enzyme that converts the testosterone into estrogen. If you can block it, you’ll prevent estrogenic effects, but you may not be able to stop other kinds of side effects from happening either. This is why it’s so important to understand the effects of both and know what to use when you want to prevent certain side effects. If you don’t want gyno, a SERM will do wonders in blocking the test from being able to bind to the enzyme. But if you want to reduce serum estrogen, again, you’ll need an AI.
Remember, just as testosterone binds to the body and creates estrogenic effects, it also produces androgenic effects as well. These would otherwise be known as effects that can cause a series of male-oriented effects to take place. This is primarily why when people take testosterone, there are stereotypical side effects that are often used mockingly. For one, the fact that many men with high test tend to go bald is no coincidence. Just as it binds to the aromatase enzyme producing estrogenic effects, testosterone also binds to the 5-alpha-reductase enzyme and produces DHT (dihydrotestosterone) as a side effect. DHT is great for tremendous strength gains and power, but it’s really bad if you want a full head of hair. This is because when DHT is produced, it forms in specific areas of the body, primarily the scalp, prostate, and skin, thereby causing various side effects when the bind occurs. In the scalp, it can trigger male pattern baldness, something that is very commonly seen in men that have the genetic trait for baldness already built-in. This is important to note because if these kinds of side effects are dealbreakers for you, then you definitely need to consider an alternative method of getting stronger from exogenous compounds. Otherwise, you’ll really have to rethink what you’re using as a supplement.
However, just like you have options in combatting the kinds of issues you face when it comes to estrogenic compounds, you have options when it comes to dealing with DHT. It’s very important to understand that when you do want to stop DHT conversion, you will still have a high likelihood of running into androgenic side effects since the androgenic effects of testosterone are so potent. For one, you can use compounds like Proscar or Dutasteride to combat the androgenic effects commonly found in DHT. Aside from male pattern baldness, oily skin, irritation, enlarged prostate, and acne are also the side effects one can experience with DHT. Very similar to the estrogenic compounds, the side effects mimic those ones you might experience had you ever dealt with the unsightly consequences of puberty as a boy.
When it comes to the use of any exogenous compound, you have to understand that you’re putting your body at risk. Whether you’re doing it for curiosity, bodybuilding, sports performance, or to enhance your quality of life, you have to be aware that whenever you choose to use an androgenic compound like testosterone, you have to be very thorough with how you use it, and especially, with how you stop using it. This may sound counter-intuitive, but this is why you need to be aware of the side effects when using any testosterone producing drug. One of the most important side effects you have to be aware of is the concept of the shutdown. A shutdown is what happens whenever you introduce a very powerful androgenic compound to your body. What happens is your body reads the introduction of the substance as it no longer having a need to produce testosterone. It then, as the name suggests, shuts down its testosterone production and instead allows you to inject yourself with the exogenous hormone. This can work for very short durations, such as if you’re running a very strong blast cycle of a steroid, but over a long period of time, this is not sustainable. What happens is your body can undergo a very troublesome period called hypogonadism, wherein the body stops producing testosterone naturally. For the long term, this can be a devastating consequence, so instead of having to deal with this, you need to be responsible with how you use compounds. When you’re done with your cycle, you have to do what’s known as PCT, or post-cycle therapy. This means you’ll have to use an AI to reduce the estrogen levels in your body, and you’ll also want to make sure you’re taking HCG, which is a naturally produced hormone that stimulates your testes to produce testosterone. Should you fail to follow this advice, you very well could be taking TRT ( testosterone replacement therapy) level doses for life in order to recalibrate your testosterone production. However, it is very rare that this happens unless horrific abuse of androgenic compounds takes place. Should you be adept in terms of swiftly engaging in using an AI and compound to restimulate production, you won’t have to worry about anything whatsoever.
Aside from the typical side effects that can more or less be a matter of inconvenience, you have to be aware of the fact that any use of androgenic compounds can also be harmful to your liver health. The cells in your liver are the cells in your body that take the longest to regenerate, meaning that if you do permanent damage to these cells, your liver may have to be transplanted. This is a very extreme example, but it can happen if you do not exercise care with your liver. Rather than letting that happen, it’s very important to understand that any sort of androgen will cause some toxicity and put stress on the lymphatic system to clean everything out. However, it should be stressed that androgens CAN be harmful to your liver and may not be depending on what you use.
In the case of test prop, you do not have to worry about liver toxicity whatsoever. For one, if you were injecting the substance, you would bypass the liver altogether. When you do ingest something orally, the substance passes through the liver to be “checked” by the system internally. What it is doing is ensuring that whatever you’ve ingested is properly synthesized and analyzed from within, and once that’s accomplished, the determination is made whether or not it’s a healthy substance that is fit to absorb. After numerous studies showing considerably high oral doses of test prop, it’s been shown that the substance is not at all hepatotoxic, in other words, it is something that is fit to be taken without fear of any liver toxicity.
It should be noted that with any androgenic compound that you use, it is possible to see a shift in your cholesterol levels. It can also affect your blood pressure. However, it should be noted that the primary reason for this effect is correlated with the feedback that you can see with estrogen levels dropping. Estrogen, as much as bad rep as it tends to get, is very important to you for ensuring you have proper cardiovascular levels. With it in place, you have to understand that your cardiovascular system will be in check. That’s why it’s very important that you don’t completely murder your estrogen levels with an AI. Rather than totally trying to phase out the estrogen in your system, consider a smaller dose to reduce it slightly, this will ensure that you can properly engage in using the androgen without compromising your cardiovascular health. However, by maintaining a good diet and promoting cardiovascular exercise, you can stave off the typical negative effects you would get in terms of cardiovascular health.
Testosterone Propionate should be administered frequently due to its short half-life. This short acting testosterone variant is injected intra-muscularly deep into the muscle using a minimum 5”8 or 1 inch sterile needle. Its important that care is taken when injected IM. Sterility is important, new needles, barrels and syringes must be used an alcohol swabs.
For low testosterone treatment, doses of 50mg are used three times per week or every other day (EOD). However, Testosterone Propionate is not a common use for hypogonadism due to the high amount of regular injections. Endocrinologists tend to lean towards longer estered Testosterone compounds such as, Testosterone Enanthate and Testosterone Cypionate as they’re administered twice per week or weekly in doses of 100-150mg for low testosterone treatment.
For performance enhancing, Testosterone Propionate is injected 50-100mg every other day, or in larger doses if the athletes or bodybuilder is more experienced. As a base of a steroidal cycle, Testosterone Propionate can be used to replace endogenous testosterone, or as a performance enhancer itself. As a performance enhancing drug (PED), 100mg every day is suggested in combination with an AI or SERM to control estrogenic side effects. Aromasin at 25mg every day or Arimidex 1mg every other day would be advised to keep estrogen levels in normal ranges.
Testosterone Propionate can be stacked with 17aa oral anabolic steroids such as, Dianabol, Winstrol and Anavar (Oxandrolone). This exogenous testosterone injectable could also be used synergistically with Trenbolone Acetate, NPP or other short acting anabolic steroids like Winstrol Depot.
Overview and History of Tren 100mg Fast Acting (trenbolone acetate)
Trenbolone Acetate (commonly abbreviated as Tren Ace, Tren A, or simply as Tren) is the most popular format of Trenbolone in use by bodybuilders and athletes today. Initially, Trenbolone was officially released for a very brief period onto the human prescription market as Trenbolone Hexahydrobenzylcarbonate under the brand name Parabolan, which was manufactured in France. Parabolan was the first and only form of Trenbolone to be ever manufactured and sold for human use. This was for a very short period during the 1990s, however, and towards the late 1990s it was pulled from the market and Trenbolone itself was officially disapproved for human use. To this day, Trenbolone is still only officially utilised as a veterinary medicine exclusively for the purpose of promoting and preserving lean mass in livestock and cattle. It is not currently approved for human use anywhere in the world, but it is under current investigation in clinical studies as a more selective anabolic steroid than others, giving it the potential for medical application[1]. This is therefore a strong indication that Trenbolone might soon see re-entry into the human prescription drug market and re-approval for human use, though it is unknown how long it might be before this happens.
Trenbolone itself is a derivative of Nandrolone, and these two anabolic steroids (Trenbolone and Nandrolone) are classified as 19-nor compounds, meaning they both lack the 19th carbon on their chemical structure (this is what characterizes a 19-nor compound, and this 19th carbon is indeed found on Testosterone and all other anabolic steroids except for those that lack it). Because of this, they are categorized also as Progestins. Although Trenbolone and Nandrolone are distinctly different from Progesterone, they are Progestins and express interaction and activity with the Progesterone receptors in the body. In any case, Trenbolone is further removed from its parent hormone Nandrolone because while the lack of Nandrolone’s 19th carbon is replaced with a hydrogen atom, Trenbolone’s lack of a 19th carbon is replaced with double bonds in order to fill in the void created by the missing 19th carbon. Trenbolone further contains a modification of carbon 11, where a hydrogen atom was removed and the remaining void is once again filled in by double-bonding with its neighbouring carbon atom. What this creates for Trenbolone are three characteristics: the first being a massive increase in the affinity for the androgen receptor, creating a very potent and strong anabolic steroid[2]. The second advantage it creates for Trenbolone is making Trenbolone completely resistant to aromatization into Estrogen. This is a stark difference from Nandrolone, which merely exhibits an increased resistance to aromatization (but it still occurs in smaller amounts). The aromatase enzyme (the enzyme responsible for the conversion of androgens into Estrogen) does not recognise Trenbolone as a proper substrate for chemical reaction. The third characteristic granted to Trenbolone by these modifications is its ability to be highly resistant to metabolism in the body.
Trenbolone Acetate itself was studied in several experiments by Roussel-UCLAF and published in 1967[3]. In the early 1970s, Trenbolone Acetate production was picked up by Hoescht in England and was marketed and sold under the brand name Finajet. Roussel in France sold Trenbolone Acetate as Finaject, and Roussel AG of Germany actually owned and controlled both pharmaceutical corporations. Finaject and Finajet both existed for a short while on the human prescription drug market as well, much in the same manner as Parabolan before they too were discontinued and disapproved for human use. Today, Trenbolone Acetate is used officially in cattle as cattle implants primarily under the brand name of FInaplix tablets/pellets, though other brands exist as well. Trenbolone Acetate’s popularity among bodybuilders and athletes only began during the 1980s, and nearly all of the Trenbolone Acetate used at that time was Finajet and Finaject smuggled into North America from Europe (often in large amounts). It quickly gained status as a very popular anabolic steroid due to its immense potency in anabolism as well as its capability to provide a ‘hard’ look to the physique without any Estrogen conversion and zero water retention as a result. Because of the brief lifespan of Trenbolone Acetate on the human prescription market as mentioned previously, importation of Trenbolone Acetate quickly came to a halt in 1987 just when the drug was reaching extreme popularity and discussion among athletes and bodybuilders.
The late 1980s and early 1990s was a period where many anabolic steroids were purposely discontinued and abandoned (such as Dianabol and several others) due to the increasing anti-steroid hysteria among the US government and the media, which prompted many pharmaceutical companies to discontinue many anabolic steroids that were known to be used and favoured by athletes rather than their medical use. Ironically, however, it was during the end of Finajet and Finaject in Europe that Trenbolone Acetate was brought to the United States in the form of cattle implantation pellets (which must be implanted with a special implantation gun), and the FDA approved this in 1987. It was not long, however, before underground labs (UGLs) and bodybuilders began obtaining these pellets and converting them for use in humans, resulting in injectable preparations or transdermal patches. Some bodybuilders and athletes would also consume the pellets orally, although this was/is a rarer occurrence. However, such a practice is not very far from reality, as Trenbolone exhibits a moderate level of absorption and bioavailability via the oral route due to its very strong resistance to metabolism in the body (higher dosing is required with this method of administration in order to compensate for the percentage lost due to metabolism, however).
It should be noted, however, that there are different brands and variants of Trenbolone Acetate available in the form of cattle implantation pellets that contain other undesirable ingredients. For example, in addition to the different variants of Finaplix tablets (Finaplix-H and Finaplix-S), there exists Revalor and Synovex tablets that contain different concentrations of Estrogen in addition to the Trenbolone Acetate. Such an addition would not be desirable for an athlete or bodybuilder, and this addition of Estrogen is designed for cattle for the purpose of increasing the marbling effect on the meat, and to alter the ratio of lean mass on the animal. Other than this, Trenbolone Acetate today is exclusively an underground product that is either manufactured by underground laboratories or home-brewed by individuals. No pharmaceutical human grade Trenbolone Acetate products exist today as of the writing of this profile (2013).
What Is Trenbolone Acetate and Why Is It So Popular?
Trenbolone Acetate is the short estered variant of Trenbolone, and it tends to be the most popular esterified variant among bodybuilders and athletes. Trenbolone is also available on the anabolic steroid black market in two other formats: Trenbolone Hexahydrobenzylcarbonate, and Trenbolone Enanthate. Trenbolone Acetate is a short-acting variant that exhibits a half-life of 3 days, and must be injected every other day at the very least in order to experience desired performance and physique changes. In comparison, Trenbolone Enanthate exhibits a half-life of approximately 7 – 10 days, and Trenbolone Hexahydrobenzylcarbonate expresses a half-life of approximately 14 days. Trenbolone Acetate tends to be the most popular among the three variants not only due to its widespread availability (especially in the form of Finaplix pellets), but also because its faster acting nature allows users to start and stop use of the drug very fast, with only a matter of days before the hormone completely clears from the body. This is commonly desired by most bodybuilders and athletes due to the fact that Trenbolone is regarded as an intermediate-advanced level anabolic steroid that carries with it potential side effects unseen in other anabolic steroids. It has therefore been labelled as a ‘harsh’ anabolic steroid, and those who use it for the first time normally elect to do so cautiously by utilising Trenbolone Acetate, and if various side effects become too concerning or prominent, the cycle can be halted and Trenbolone Acetate would clear from the body fairly quickly. This is different from the Enanthate or Hexahydrobenzylcarbonate variant, where clearance from the body can require 2 weeks or even longer (for the Hex variant) before the hormone totally clears out of the body.
This hormone is revered for its ability to be utilised for pretty much any goal: strength gaining, bulking, mass gaining, lean mass gaining, cutting, fat loss, etc. Trenbolone exhibits an anabolic rating of 500, which is 5 times the anabolic strength of Testosterone. It also exhibits an androgenic rating of 500, also 5 times the androgenic strength of Testosterone. This makes Trenbolone Acetate a very powerful and formidable anabolic steroid to be respected, where high doses are not required to elicit positive results. Trenbolone Acetate can be utilised to gain large amounts of muscle mass without the water retention and bloating (provided the user is utilising low doses of other aromatizable compounds, and is eating a caloric surplus). It can also be utilised to lean out the physique and shed body fat faster than any other anabolic steroid if the user engages in a caloric deficit and appropriate training regime. Because of Trenbolone’s extremely potent nutrient partitioning capabilities, it can be used to effectively put on significant mass or be used to cut body fat, and is considered an essential addition to pre-contest cycles. It is often referred to as “the nectar of the Gods” due to its incredible capabilities.
Tren Acetate tends to bring with it an aura of intimidation to many users, however. This is due to the lore and legend surrounding some of its unique and often termed ‘harsh’ side effects. This will be covered very shortly, but it should be established here and now to all readers that although there is some truth to Trenbolone’s legend of being a ‘harsh anabolic steroid’, there is much exaggeration and myth surrounding many of these claims and stories as well.
How Does Trenbolone Acetate Work and How Is It Best Used?
As previously mentioned, Trenbolone Acetate is perhaps the most versatile anabolic steroid next to Testosterone itself. It can be utilised in any cycle type, and compliments any other compounds very well. It should always be utilised with Testosterone, however, as its Progestogenic activity can cause impairment of the libido and other proper functions that Testosterone is responsible for governing. Therefore, many users who elect to use Tren Ace on its own commonly experience sexual dysfunction and anorgasmia (the inability to orgasm). Testosterone even at a TRT (Testosterone Replacement Therapy) dose of 100mg per week should suffice in assisting the body supportively during Tren use.
Trenbolone Acetate Side Effects
Trenbolone Acetate carries with it many of the standard potential side effects that all anabolic steroids in general carry with them (for example: negative cholesterol alterations, cardiovascular effects, endogenous Testosterone and HPTA suppression/shutdown, etc.). However, what should be the focal point here of this section of this profile are the unique side effects that are associated with Trenbolone, which are often referred to as ‘harsh’ and come with plenty of absurd lore, legend, myth, and rumour. Upon first use of Trenbolone Acetate in the 1980s, not much knowledge was known about it and therefore many athletes and bodybuilders were left up to their own suspicions and curiosity, but today the amount of scientific and clinical knowledge is far greater, which should clarify many of the myths and rumours surrounding Tren.
Unique side effects associated with Trenbolone Acetate include a moderate to severe coughing fit during and shortly after injecting the compound. This tends to occur more frequently with Trenbolone Acetate than it does with other forms of Trenbolone, likely due to the faster release of the compound and other unknown factors. The cause of this ‘Tren cough’ is largely unknown, but some valid and accurate hypotheses include the fact that Trenbolone itself causes varying degrees of anaphylactic reactions in the bronchial pathways, as well as some of the compound seeping into punctured capillaries/veins during the injection, which irritate the lungs. What results is a coughing fit that can range from very mild to severe and lasts only several minutes. Injecting the compound slowly tends to eliminate or reduce the intensity of the coughing, and many times this does not occur at all. It should be noted that a coughing fit can occur from any anabolic steroid injected that seeps into ruptured blood vessels, and that a coughing fit does not mean that the Trenbolone is necessarily ‘legitimate’ or ‘good to go’.
Trenbolone is known for causing severe sweating, especially during nighttime sleeping. This is also accompanied by insomnia, either in the form of being unable to fall asleep or the intermittent waking throughout the night accompanied with tossing and turning. The insomnia, commonly dubbed as ‘Trensomnia’, is thought to be due to Trenbolone’s increased influence and activity on the nervous system than most other anabolic steroids, which can tend to increase the excitability of the nervous system and disrupt quality sleep patterns. The cause of the severe perspiration and sweating associated with Tren Acetate is currently unknown, though some hypotheses claim that the sweating is induced by Trenbolone’s capability to increase the metabolism (and thus heat generation) at certain times of the day.
Lastly, Trenbolone is known for its ability to induce larger amounts of aggression, anger, and impatientness in some users. This is due to Trenbolone’s increased activity on the central nervous system, and is due also in very large part to its extremely strong androgenic strength. It is highly advised that those who have problems with their temper or patience to take responsible action and avoid the use of Trenbolone at all costs, or learn to exhibit self-control when one’s anger, temper, or patience gets the best of them. It is irresponsible to utilise a very strong compound such as Trenbolone (and knowing full well all of its potential effects) and allow oneself to get angry and land in trouble, and instead blaming the anabolic steroid rather than themselves for exercising poor self-responsibility. Tren is a drug, a hormone to be respected. Respect the hormone and it will respect you.
Overview and History of Masteron 100mg Fast Acting (drostanolone propionate)
Masteron is the trade name for the anabolic steroid Drostanolone. Materon is an injectable oil-based anabolic steroid, and is derived from Dihydrotestosterone (DHT), which makes Masteron a member of the DHT-derived family of anabolic steroid derivatives and analogues. Essentially, all anabolic steroid analogues and derivatives are all modifications in one way or another of the three primary anabolic steroids naturally found in all humans: Testosterone, Dihydrotestosterone, and Nandrolone. In this case, Masteron’s progenitor (or parent) hormone is Dihydrotestosterone. Other anabolic steroids that belong in this family of DHT-derivatives include: Anavar, Winstrol, Anadrol, Primobolan, and various others. Masteron is not regarded as a very strong anabolic steroid but neither is it a weak one. Its anabolic strength is generally regarded as moderate at best (anabolic rating of 62 – 130), while its androgenic strength is fairly low (25 – 40). This demonstrates a stark difference when compared to Testosterone, which is the number one natural and original anabolic steroid, and is used as the reference measuring bar by which all other anabolic steroids are compared to and measured against. Testosterone in comparison holds an anabolic and androgenic strength rating of 100 for both respectively.
Masteron’s details (as Drostanolone) were first released and published in 1959[1]. The origins of this compound are quite interesting, as Syntex had synthesized and developed this anabolic steroid. Syntex was also known for the development of other popular anabolic steroids as well, such as Anadrol and Methyldrostanolone (AKA Superdrol). It would not be until about 10 years later after the publishing of its details that Masteron would finally be released onto the market. Lilly and Syntex had worked together in the development and marketing of different pharmaceuticals, and both companies had an agreement that both entities would share research and development (R&D) resources and costs with the trade-off that one of the companies would obtain the rights to the drug. It was Lilly that ended up marketing Masteron under the brand name known as Drolban on the American market. Syntex also marketed this anabolic steroid, only they would look after its marketing and distribution on the international market instead.
Masteron was approved by the FDA at first as an antineoplastic agent in the treatment of female breast cancer patients. Masteron in particular fit very well into this role, as its lower and weaker androgenic strength rating in comparison to Testosterone could prove to be very beneficial in female users, as the incidence of virilization symptoms would be less prominent with Masteron than many other anabolic steroids which are known to possess strong androgenic strength ratings. Even the prescription information and guidelines expounded this fact, stating that there is far less of a probability of developing virilization with Masteron in comparison to equal Testosterone Propionate doses. However, the problem here was that the initial prescription guidelines for females was that of 300mg weekly of Masteron, which evidently proved to be too high of a dose for females as evidenced by the fact that virilization did occur in many patients at that dose. Virilization had also become an issue in female patients that had been administered Masteron in the long term.
Masteron’s popularity with bodybuilders and athletes did not begin until the 1970s and increased into the 1980s. As more effective breast cancer treatments were discovered and developed, Masteron began to lose its value in the medical field, and many different pharmaceutical manufacturers began to slowly discontinue sale and production of this compound during this time. Drolban itself was officially pulled from the American market in the late 1980s, and two other branded Masteron preparations were soon after pulled from the market as well. Masteron today still remains on the list of approved medications, but it is not currently being manufactured, and therefore not being sold on American (or any Western) markets.
Chemical Characteristics of Masteron
The specific name for Masteron is actually Dromostanolone (Drostanolone was a slightly more abbreviated name given to the compound shortly after its release). As mentioned previously, it is a modified derivative of DHT (Dihydrotestosterone), placing it into the family of DHT-derivatives and analogues. Masteron is a modified form of DHT, where a methyl group at the 2ndcarbon (known as carbon alpha) atom. This modification is what is known to be responsible for the slight anabolic strength increase in comparison to Testosterone. This methyl group addition increases the anabolic strength by way of granting Masteron an increased resistance to being metabolized into inactive metabolites by the enzyme 3-hydroxysteroid dehydrogenase. This enzyme is present in large quantities in muscle tissue, and is the enzyme that serves to metabolize any DHT that enters muscle tissue into two inactive metabolites: 3-Alpha Androstanediol and 3-Beta Androstanediol that are non-anabolic what so ever in muscle tissue. This is therefore the reason as to why DHT is not anabolic in muscle tissue at all, and many chemists and biologists believe that if the enzyme 3-hydroxysteroid dehydrogenase did not exist in muscle tissue, that DHT would actually be a very potent and powerful anabolic steroid. In any case, Masteron’s methyl group addition to alpha carbon 2 effectively eliminates its ability to be metabolized by this enzyme.
There exist two different variants of Masteron: Drostanolone Propionate, and Drostanolone Enanthate. The most popular variant is the Propionate variant, followed in popularity by the Enanthate variant. The explanation here will use Drostanolone Propionate as the example. Specifically, ‘Propionate’ is Propanoic acid, but once bound to Masteron it is properly referred to in chemistry as an ester bond (or ester linkage). Propanoic acid is bonded to the 17-beta hydroxyl group on the Drostanolone (Masteron) chemical structure. The addition of this ester modifies the hormone’s half-life and release rate, providing a much longer extended release and half-life than if the hormone was not esterified. The primary reason for the augmentation of its half-life and release rate is because once Drostanolone Propionate enters the bloodstream, enzymes in the body will break the bond between the ester and the hormone, which takes varying amounts of time (the time taken for the bonds to be broken is dependent on the size of the ester – the longer and larger it is, the longer it will take). The end result is that the ester is removed from the hormone by enzymes, and what is left is pure Masteron (or any anabolic steroid that was previously esterified) that is now free to do its work in the body. This process of enzymes cleaving off the ester from the Testosterone molecule is what is responsible for the slower release rates and extended half-lives.
As a result, Drostanolone Propionate possesses a half-life of 2.5 days, and Drostanolone Enanthate possesses a half-life of 10 days. Esterification does nothing to modify the effects and characteristics of the hormone aside from augmenting the hormone’s release rates and half-lives.
Properties of Masteron
Because Masteron is a DHT-derivative, it retains some of the same characteristics as its parent hormone, one of which is its inability to interact with the aromatase enzyme. The aromatase enzyme is the enzyme responsible for the conversion of androgens into Estrogen, of which Masteron is invulnerable to this process. Therefore, Masteron will exhibit no Estrogenic side effects at any dose, making Masteron completely void of the following risks: water retention and bloating, elevated blood pressure (as a result of water retention), possible fat gain/retention, and gynecomastia. Individuals using Masteron will only experience lean mass gains without the addition of water weight, which would otherwise serve to create a very puffy, soft, and bloated looking physique. It is therefore an anabolic steroid preferred by the majority of bodybuilders and athletes as a ‘cutting’ compound considered very useful for pre-contest cycles and fat loss and cutting phases.
Due to its low to moderate anabolic strength, Masteron is not regarded as being a very good mass addition or bulking compound, and in fact many experienced anabolic steroid users suggest that due to its higher price and its moderate anabolic strength, it is only of real value to competitive bodybuilders who wish to achieve a very hardened and ‘chiseled’ look to the physique once on-stage in a show. When stacked with other particular compounds, Masteron has been shown to bring out a ‘ripped’ physique to an even greater deal. However, these ‘hardening’ properties of Masteron do not exhibit themselves in the user unless he or she possesses a low enough body fat percentage to be able to allow these hardening effects to become visible. This leads to the next major property of Masteron.
Masteron has been demonstrated as being a moderate aromatase inhibitor, as well as possibly acting to block Estrogen at receptor sites on breast tissue[2] [3]. This is the reason for Masteron’s original and primary use as an advanced breast cancer treatment drug. This is also the reason as to why Masteron has been explained by many experienced users as having a ‘hardening’ and ‘chiseling’ effect on the physique when the body is very lean (under 10% body fat). Masteron works to inhibit the aromatase enzyme, thereby eliminating the ability for estrogen to be formed from aromatizable anabolic steroids through the process of aromatization. Essentially, this effectively reduces any water retention as Estrogen levels continue to decline from increasing numbers of disabled aromatase enzymes.
Masteron Side Effects
Masteron is regarded by the bodybuilding community as being one of the ‘mild’ anabolic steroids when it comes to side effects. This is due in large part to the fact that Masteron is a DHT-derivative. Having been derived from DHT, it therefore possesses all of the same (or similar) attributes and features that DHT does. This includes the inability to interact with the aromatase enzyme, and therefore be completely void of any Estrogen-related side effects.
As previously mentioned, Masteron is totally void of any estrogenic side effects by virtue of the fact that it is a DHT-derivative. Not only does it completely avoid aromatization (conversion into Estrogen), evidence suggests that it behaves as a mild aromatase inhibitor as well. Side effects resultant of Estrogen buildup (such as water retention, bloating, fat retention and gain, and the development of gynecomastia) are completely avoided or reduced with the use of Masteron.
Though Masteron holds a weaker androgenic strength rating than Testosterone itself, androgenic side effects are still indeed possible with this compound, especially among those who may be particularly sensitive. Masteron side effects that include androgenic side effects include: an increase in oily skin (as a result of increased sebum production/secretion), increased facial hair and bodily hair growth, as well as the increased risk of triggering MPB (Male Pattern Baldness) in those that are genetically sensitive or predisposed to it. Virilization (the development of male characteristics in women) is also a risk with female use, though its use in female breast cancer patients should attest to its acceptable nature as a female-use compound.
Masteron side effects in particular include greater negative impacts on cholesterol and the cardiovascular system than some other compounds. This is largely due to Masteron’s anti-estrogenic capabilities in the body. Its ability to reduce serum levels of Estrogen results in measurable reductions in HDL (‘good’) cholesterol, and increases LDL (‘bad’) cholesterol[4].
Masteron exhibits no hepatotoxicity (liver toxicity), but like any anabolic steroid, it does contribute to suppression/shutdown of the HPTA, thereby reducing endogenous production of Testosterone.
Masteron Cycles and Uses
Masteron cycles tend to be quite limited in their dynamic and application. This is because of the nature of the compound being unfavorable for bulking, strength gain, and the like. Unfortunately, as a cutting or fat loss agent, there are much better anabolic steroids in existence at the disposal of the individual than Masteron. Therefore, the only particular Masteron cycles that bodybuilders tend to use involve pre-contest and cutting / fat-loss cycles. Even in cutting or fat loss cycles, Masteron is usually not a key-role compound involved.
The cycle length of Masteron cycles are usually in the range of 8 – 10 weeks, mostly due to its short-ester nature. Some bodybuilders will elect to utilize Masteron only within the final 2 – 4 weeks of a cycle leading up into a show or a photoshoot, only to gain advantage of its physique enhancement abilities. This generally looks like a cycle performed for 10 weeks, with compounds such as Testosterone Propionate, Trenbolone Acetate, and Anavar being used. Towards the 6 or 8-week mark of said cycle, Masteron would be included into the mix (alongside perhaps a removal of one of the other compounds), and run right to the end of the 10th week.
For more traditional Masteron cycles, its use as a fat loss / cutting compound would involve consistent use over a 8 – 10 week period alongside compounds of a similar nature, such as injectable Winstrol, Testosterone Propionate, and perhaps Trenbolone Acetate or the oral variant of Winstrol.
Masteron Dosages and Administration
Within the medical arena, Masteron was utilized in the treatment of female breast cancer patients. Towards this end, prescription guidelines for Masteron dosages would call for 100mg three times per week, for a grand total of 300mg/week. The duration of this treatment was recommended to be 8 weeks at a minimum. By the 8 – 12-week mark, the physician would provide an assessment of the patient and their progress, and based upon the progress and the prognosis, Masteron may be utilized indefinitely in the treatment of the cancer. It is worth noting that 300mg/week, in retrospect, is far too much for female use and was even admitted somewhat by the medical establishment due to the observation of virilization becoming a frequent issue among patients. Female athletes and bodybuilders would find 50 – 100mg per week a safe and acceptable dosage.
For athletic and bodybuilding purposes for male users, Masteron dosages are in the range of 200 – 400mg per week, and the lower end of this range (200mg) is commonly utilized for pre-contest preparation and cycles. Because of the specialization of Masteron being an aesthetic physique enhancing compound, intermediate and even advanced users tend not to venture higher than the 400mg/week mark. It must be remembered that Masteron is a weak compound where the addition of strength, mass, and muscle is concerned, and there are more effective (and cheaper) compounds for this purpose.
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